Motif ID: HOX{A5,B5}.p2

Z-value: 0.882


Transcription factors associated with HOX{A5,B5}.p2:

Gene SymbolEntrez IDGene Name
HOXA5 3202 homeobox A5
HOXB5 3215 homeobox B5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HOXB5chr17_-_440260420.514.1e-02Click!
HOXA5chr7_-_271497500.136.2e-01Click!


Activity profile for motif HOX{A5,B5}.p2.

activity profile for motif HOX{A5,B5}.p2


Sorted Z-values histogram for motif HOX{A5,B5}.p2

Sorted Z-values for motif HOX{A5,B5}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A5,B5}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_109600709 1.433 COL4A1
collagen, type IV, alpha 1
chr15_+_72005847 1.409 LOXL1
lysyl oxidase-like 1
chr15_+_72005864 1.397 LOXL1
lysyl oxidase-like 1
chr15_+_72005839 1.389 NM_005576
LOXL1
lysyl oxidase-like 1
chrX_+_135058402 1.200 NM_001159700
FHL1
four and a half LIM domains 1
chr1_+_114323552 1.068 NM_020190
OLFML3
olfactomedin-like 3
chr5_+_17270474 1.066 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr11_-_2116048 0.959 IGF2
insulin-like growth factor 2 (somatomedin A)
chr4_-_115120251 0.917 NM_024590
ARSJ
arylsulfatase family, member J
chrX_+_51562894 0.908 NM_001005332
MAGED1
melanoma antigen family D, 1
chr12_-_54387732 0.867 ITGA7
integrin, alpha 7
chr2_+_30223372 0.857 YPEL5
yippee-like 5 (Drosophila)
chr1_-_161379606 0.854 RGS5
regulator of G-protein signaling 5
chr21_-_27261276 0.845 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chrX_+_99786044 0.840 SRPX2
sushi-repeat containing protein, X-linked 2
chr3_-_51968995 0.834 PCBP4
poly(rC) binding protein 4
chr12_-_90096275 0.818 NM_133504
NM_133505
NM_133506
NM_133507
DCN



decorin



chr19_-_54835162 0.795 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr8_+_26569709 0.789 DPYSL2
dihydropyrimidinase-like 2
chr2_-_210888010 0.774 NM_079420
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr12_-_105057940 0.764 NM_014840
NUAK1
NUAK family, SNF1-like kinase, 1
chr13_+_113574925 0.736 NM_001143945
GAS6
growth arrest-specific 6
chr6_+_121798443 0.729 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chrX_+_54851500 0.722 NM_014599
MAGED2
melanoma antigen family D, 2
chrX_+_54850832 0.709 NM_177433
MAGED2
melanoma antigen family D, 2
chr4_+_40953652 0.706 NM_004181
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr5_+_148501178 0.688 NM_014945
ABLIM3
actin binding LIM protein family, member 3
chr2_+_30223304 0.676 YPEL5
yippee-like 5 (Drosophila)
chr20_+_19863716 0.670 RIN2
Ras and Rab interactor 2
chr3_-_129023850 0.662 NM_007283
MGLL
monoglyceride lipase
chr2_+_30223253 0.658 NM_001127399
NM_001127400
NM_001127401
NM_016061
YPEL5



yippee-like 5 (Drosophila)



chr19_-_53444733 0.652 NM_001184901
NM_001184903
NM_014959
CARD8


caspase recruitment domain family, member 8


chr15_+_22772545 0.607 SNRPN
small nuclear ribonucleoprotein polypeptide N
chr12_-_6668680 0.584 ZNF384
zinc finger protein 384
chrX_+_100220491 0.581 NM_021637
TMEM35
transmembrane protein 35
chr4_-_81213207 0.578


chr4_+_40953666 0.571 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr8_-_93177057 0.553 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr12_+_51979721 0.543 NM_021640
C12orf10
chromosome 12 open reading frame 10
chr5_-_150501393 0.521 NM_001193544
ANXA6
annexin A6
chr17_+_35853177 0.489 NM_001552
IGFBP4
insulin-like growth factor binding protein 4
chr11_-_111287657 0.480 NM_001885
CRYAB
crystallin, alpha B
chr19_-_56919032 0.479 NM_001523
HAS1
hyaluronan synthase 1
chr4_+_40953698 0.476 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr13_-_48005251 0.462 NM_001268
RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr8_-_93176618 0.457 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr12_+_7038240 0.448 NM_001734
NM_201442
C1S

complement component 1, s subcomponent

chrX_+_102770303 0.445 NM_001006640
TCEAL1
transcription elongation factor A (SII)-like 1
chr6_+_36752244 0.432 NM_078467
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr12_+_107433179 0.425 NM_007076
FICD
FIC domain containing
chr1_+_148511806 0.424 NM_024579
C1orf54
chromosome 1 open reading frame 54
chr5_-_149515331 0.418 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chrY_+_21146998 0.417 NM_004681
EIF1AY
eukaryotic translation initiation factor 1A, Y-linked
chrX_+_99785818 0.413 NM_014467
SRPX2
sushi-repeat containing protein, X-linked 2
chr3_-_122862447 0.410 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr19_+_39437292 0.400 NM_014686
KIAA0355
KIAA0355
chr7_-_47588266 0.397 TNS3
tensin 3
chr4_+_55218663 0.392 NM_000222
NM_001093772
KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr2_+_8739563 0.386 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chrX_-_99778340 0.386 NM_003270
TSPAN6
tetraspanin 6
chr13_-_48005358 0.380 RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr6_-_24985432 0.378 NM_015864
FAM65B
family with sequence similarity 65, member B
chr3_-_55496370 0.372 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr6_-_6265874 0.369 F13A1
coagulation factor XIII, A1 polypeptide
chr11_-_27677755 0.357 NM_170734
BDNF
brain-derived neurotrophic factor
chr13_-_32757835 0.356 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr16_+_67778441 0.352 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr16_-_48418418 0.352 NM_015069
ZNF423
zinc finger protein 423
chr2_-_217248967 0.338 IGFBP5
insulin-like growth factor binding protein 5
chr12_+_55201854 0.335 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr3_+_23961739 0.327 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr8_+_26427378 0.325 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr3_+_11153778 0.312 NM_001098213
HRH1
histamine receptor H1
chrX_-_37964924 0.308 NM_001170750
NM_001170751
NM_001170752
NM_006307
SRPX



sushi-repeat containing protein, X-linked



chrX_-_153290697 0.307 NM_006730
DNASE1L1
deoxyribonuclease I-like 1
chr22_+_34109095 0.301 HMOX1
heme oxygenase (decycling) 1
chr17_+_7563763 0.301 NM_020877
DNAH2
dynein, axonemal, heavy chain 2
chr11_-_116608020 0.299 NM_004716
PCSK7
proprotein convertase subtilisin/kexin type 7
chr1_-_201420927 0.298 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr1_-_89364273 0.298 NM_004120
GBP2
guanylate binding protein 2, interferon-inducible
chr15_+_57146353 0.293 RNF111
ring finger protein 111
chr1_-_31003260 0.293 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr9_-_134809816 0.292 NM_000368
NM_001162426
NM_001162427
TSC1


tuberous sclerosis 1


chr2_-_242096122 0.290 STK25
serine/threonine kinase 25
chr19_-_8548232 0.289 MYO1F
myosin IF
chr10_-_75080784 0.284 NM_024875
SYNPO2L
synaptopodin 2-like
chr14_-_22354851 0.283 NM_001126105
NM_003982
SLC7A7

solute carrier family 7 (cationic amino acid transporter, y+ system), member 7

chr3_+_49002285 0.283 NM_177938
NM_177939
P4HTM

prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)

chr1_-_151867338 0.280 NM_005979
S100A13
S100 calcium binding protein A13
chrX_-_119487164 0.276 LAMP2
lysosomal-associated membrane protein 2
chr4_-_110942783 0.273 NM_000204
CFI
complement factor I
chrX_-_104352005 0.273 NM_031274
TEX13A
testis expressed 13A
chrX_+_102517909 0.269 NM_206915
NM_206917
NGFRAP1

nerve growth factor receptor (TNFRSF16) associated protein 1

chrX_-_119487096 0.259 LAMP2
lysosomal-associated membrane protein 2
chr20_-_43889339 0.255 NM_003279
TNNC2
troponin C type 2 (fast)
chr3_+_51397731 0.250 NM_006010
MANF
mesencephalic astrocyte-derived neurotrophic factor
chr10_+_102285562 0.249 NM_017902
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr9_+_34980715 0.249 DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr19_+_46416938 0.248 NM_001699
NM_021913
AXL

AXL receptor tyrosine kinase

chr18_-_51406841 0.247 NM_001083962
NM_003199
TCF4

transcription factor 4

chr8_+_38704860 0.246 NM_001146216
TACC1
transforming, acidic coiled-coil containing protein 1
chr7_+_45899621 0.244


chrM_+_12283 0.242


chr10_+_102285690 0.240 HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr3_+_51397756 0.236 MANF
mesencephalic astrocyte-derived neurotrophic factor
chr8_+_97575052 0.236 NM_002998
SDC2
syndecan 2
chr12_-_6668787 0.234 NM_001039918
NM_133476
ZNF384

zinc finger protein 384

chr16_-_30993004 0.233 NM_024706
ZNF668
zinc finger protein 668
chr1_+_201711578 0.232 PRELP
proline/arginine-rich end leucine-rich repeat protein
chr1_-_153444304 0.228 NM_007112
THBS3
thrombospondin 3
chrX_+_102770547 0.227 NM_001006639
NM_004780
TCEAL1

transcription elongation factor A (SII)-like 1

chr2_+_170044194 0.227 NM_152384
BBS5
Bardet-Biedl syndrome 5
chr11_-_6633427 0.226 NM_003737
DCHS1
dachsous 1 (Drosophila)
chr14_-_22974707 0.225 NM_000257
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr10_-_74526596 0.223 P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
chrX_-_128485062 0.220 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr17_-_31831093 0.218 NM_001123392
NM_032258
TBC1D3C
TBC1D3G
TBC1D3
TBC1D3H
TBC1D3F
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3
TBC1 domain family, member 3H
TBC1 domain family, member 3F
chr1_+_148388870 0.216 PLEKHO1
pleckstrin homology domain containing, family O member 1
chr10_-_118022965 0.215 NM_005264
GFRA1
GDNF family receptor alpha 1
chrX_+_7147471 0.215 NM_000351
STS
steroid sulfatase (microsomal), isozyme S
chr11_-_116607968 0.212 PCSK7
proprotein convertase subtilisin/kexin type 7
chr5_+_149549712 0.212 NM_014228
SLC6A7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr7_+_90063543 0.212 CDK14
cyclin-dependent kinase 14
chr6_-_16869579 0.211 NM_000332
NM_001128164
ATXN1

ataxin 1

chr15_+_41597097 0.210 NM_002373
MAP1A
microtubule-associated protein 1A
chr22_-_37858871 0.210 CBX7
chromobox homolog 7
chr6_-_32299757 0.201 NM_004557
NOTCH4
notch 4
chr13_-_71339313 0.200 NM_004392
NM_080759
NM_080760
DACH1


dachshund homolog 1 (Drosophila)


chr17_+_39503623 0.198 NM_138387
G6PC3
glucose 6 phosphatase, catalytic, 3
chr11_+_5574440 0.198 NM_001003818
NM_001198644
NM_001198645
NM_001003819
TRIM6


TRIM6-TRIM34
tripartite motif containing 6


TRIM6-TRIM34 readthrough
chr17_-_43470134 0.196 NM_016429
COPZ2
coatomer protein complex, subunit zeta 2
chr2_+_102136833 0.195 NM_000877
IL1R1
interleukin 1 receptor, type I
chr22_+_29333069 0.195 NM_000355
NM_001184726
TCN2

transcobalamin II

chr5_-_94250357 0.194 MCTP1
multiple C2 domains, transmembrane 1
chr19_-_12128528 0.193 NM_145233
ZNF625-ZNF20
ZNF625
ZNF625-ZNF20 read-through transcript
zinc finger protein 625
chr7_-_94123413 0.193 NM_001099400
NM_001099401
NM_003919
SGCE


sarcoglycan, epsilon


chr17_-_31337798 0.193 NM_032962
NM_032963
CCL14

chemokine (C-C motif) ligand 14

chr3_-_115960807 0.192 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr22_-_35938298 0.192 NM_001051
SSTR3
somatostatin receptor 3
chr18_-_51406359 0.190 TCF4
transcription factor 4
chr14_-_67353046 0.190 NM_015346
ZFYVE26
zinc finger, FYVE domain containing 26
chr1_+_202000906 0.190 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr2_-_47022406 0.188 NM_001171508
NM_001171511
MCFD2

multiple coagulation factor deficiency 2

chr1_-_31003181 0.187 LAPTM5
lysosomal protein transmembrane 5
chr5_+_34720368 0.187 NM_001145521
NM_001145525
RAI14

retinoic acid induced 14

chr1_-_152225312 0.187 NM_002870
RAB13
RAB13, member RAS oncogene family
chr5_+_179180517 0.187 SQSTM1
sequestosome 1
chr1_+_160868822 0.187 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chr16_-_65984836 0.186 NM_015964
NM_016140
TPPP3

tubulin polymerization-promoting protein family member 3

chr9_+_137107007 0.186 OLFM1
olfactomedin 1
chr5_-_68652055 0.185 NM_176816
CCDC125
coiled-coil domain containing 125
chr6_-_6265896 0.185 NM_000129
F13A1
coagulation factor XIII, A1 polypeptide
chr7_-_94123308 0.184 SGCE
sarcoglycan, epsilon
chr14_-_22354389 0.183 SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr9_+_130427988 0.182 SPTAN1
spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
chr13_+_57103944 0.182 PCDH17
protocadherin 17
chr12_-_9159780 0.182 A2M
alpha-2-macroglobulin
chr3_-_55490401 0.181 WNT5A
wingless-type MMTV integration site family, member 5A
chr17_-_31616071 0.180 NM_001001418
NM_032258
TBC1D3B
TBC1D3C
TBC1D3G
TBC1D3F
TBC1 domain family, member 3B
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3F
chr5_+_147775652 0.179 FBXO38
F-box protein 38
chr21_+_46367216 0.178 COL6A2
collagen, type VI, alpha 2
chr3_+_9950474 0.176 CRELD1
cysteine-rich with EGF-like domains 1
chr17_-_61253122 0.175 NM_001037325
CCDC46
coiled-coil domain containing 46
chr7_-_94123362 0.175 SGCE
sarcoglycan, epsilon
chr1_-_36338436 0.172 NM_005202
COL8A2
collagen, type VIII, alpha 2
chr10_-_95231933 0.171 NM_013451
NM_133337
MYOF

myoferlin

chrX_+_102518764 0.169 NM_014380
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chrX_+_102518064 0.168 NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr4_-_149582948 0.167 NM_000901
NM_001166104
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr10_-_44794146 0.167 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr19_+_52908412 0.163 NM_014601
EHD2
EH-domain containing 2
chr1_+_148388719 0.162 NM_016274
PLEKHO1
pleckstrin homology domain containing, family O member 1
chr17_-_20886680 0.162 NM_015276
USP22
ubiquitin specific peptidase 22
chr17_-_31528027 0.161 NM_001001417
TBC1D3B
TBC1D3C
TBC1D3G
TBC1D3F
TBC1 domain family, member 3B
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3F
chrX_-_64112993 0.161 NM_001178033
NM_018684
ZC4H2

zinc finger, C4H2 domain containing

chr17_-_74432671 0.159 TIMP2
TIMP metallopeptidase inhibitor 2
chr1_-_151866593 0.159 NM_001024211
S100A13
S100 calcium binding protein A13
chr8_+_38763878 0.156 NM_001122824
NM_006283
TACC1

transforming, acidic coiled-coil containing protein 1

chr17_+_37098668 0.155 EIF1
eukaryotic translation initiation factor 1
chr7_+_142768916 0.155 ZYX
zyxin
chr1_-_182990619 0.155 EDEM3
ER degradation enhancer, mannosidase alpha-like 3
chr2_+_233961538 0.155 NM_003648
DGKD
diacylglycerol kinase, delta 130kDa
chr19_-_58449752 0.154 ZNF677
zinc finger protein 677
chr4_-_186970366 0.154 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr1_+_157246305 0.152 NM_005531
IFI16
interferon, gamma-inducible protein 16
chr3_+_9950513 0.149 NM_015513
NM_001031717
NM_001077415
CRELD1


cysteine-rich with EGF-like domains 1


chr9_+_27099138 0.147 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr17_-_33552166 0.146 NM_001123391
NM_032258
TBC1D3C
TBC1D3G
TBC1D3
TBC1D3F
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3
TBC1 domain family, member 3F
chr8_-_141536992 0.146 TRAPPC9
trafficking protein particle complex 9
chrX_-_107112244 0.146 NM_031273
TEX13B
testis expressed 13B
chr5_+_150000394 0.143 NM_001109974
NM_007286
SYNPO

synaptopodin

chr17_-_33602374 0.142 NM_032258
TBC1D3C
TBC1D3G
TBC1D3
TBC1D3F
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3
TBC1 domain family, member 3F
chr15_+_30797466 0.141 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chr14_-_22354457 0.140 SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr6_-_47030492 0.140 NM_015234
GPR116
G protein-coupled receptor 116
chr7_-_81237162 0.140 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr22_-_49041786 0.140 MAPK12
mitogen-activated protein kinase 12
chr10_-_74526662 0.139 NM_000917
NM_001017962
NM_001142595
NM_001142596
P4HA1



prolyl 4-hydroxylase, alpha polypeptide I



chr9_-_34610499 0.138 DCTN3
dynactin 3 (p22)
chr4_-_77353713 0.137 SCARB2
scavenger receptor class B, member 2

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.68 2.79e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.63 3.67e-02 GO:0031982 vesicle
1.64 4.98e-02 GO:0031988 membrane-bounded vesicle

Nothing significant found in function category.